Cognitive Behavioral Therapy in Primary Care for Youth Declining Antidepressants: A Randomized Trial.

ABSTRACT: Health care providers have few alternatives for youth depression other than antidepressants. We examined whether brief cognitive behavioral therapy (CBT) is a viable alternative in primary care. A total of 212 adolescents aged 12 to 18 with major depression who had recently declined or quickly discontinued new antidepressant treatment were randomized to self-selected treatment as usual (TAU) control condition or TAU plus brief individual CBT. Blinded evaluators followed youth for 2 years. The primary outcome was time to major depression diagnostic recovery. CBT was superior to the control condition on the primary outcome of time to diagnostic recovery from major depression, with number needed to treat from 4 to 10 across follow-up. A similar CBT advantage was found for time to depression d

SUBMITTER: Clarke G 

PROVIDER: S-EPMC4845864 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature