A Multi-Site Study of Norovirus Molecular Epidemiology in Australia and New Zealand, 2013-2014.

ABSTRACT:

Background

Norovirus (NoV) is the major cause of acute gastroenteritis across all age groups. In particular, variants of genogroup II, genotype 4 (GII.4) have been associated with epidemics globally, occurring approximately every three years. The pandemic GII.4 variant, Sydney 2012, was first reported in early 2012 and soon became the predominant circulating NoV strain globally. Despite its broad impact, both clinically and economically, our understanding of the fundamental diversity and mechanisms by which new NoV strains emerge remains limited. In this study, we describe the molecular epidemiological trends of NoV-associated acute gastroenteritis in Australia and New Zealand between January 2013 and June 2014.

Methodology

Overall, 647 NoV-positive clinical faecal samples f

SUBMITTER: Lim KL 

PROVIDER: S-EPMC4846056 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature