Hematoma Locations Predicting Delirium Symptoms After Intracerebral Hemorrhage.

ABSTRACT:

Background

Delirium symptoms are associated with later worse functional outcomes and long-term cognitive impairments, but the neuroanatomical basis for delirium symptoms in patients with acute brain injury is currently uncertain. We tested the hypothesis that hematoma location is predictive of delirium symptoms in patients with intracerebral hemorrhage, a model disease where patients are typically not sedated or bacteremic.

Methods

We prospectively identified 90 patients with intracerebral hemorrhage who underwent routine twice-daily screening for delirium symptoms with a validated examination. Voxel-based lesion-symptom mapping with acute computed tomography was used to identify hematoma locations associated with delirium symptoms (N = 89).

Results

Acute delirium sym

SUBMITTER: Naidech AM 

PROVIDER: S-EPMC4846589 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature