Once-Monthly Continuous Erythropoietin Receptor Activator (C.E.R.A.) in Patients with Hemodialysis-Dependent Chronic Kidney Disease: Pooled Data from Phase III Trials.

ABSTRACT:

Introduction

Erythropoiesis-stimulating agents and iron are commonly used in patients with chronic kidney disease with the aim of correcting anemia and maintaining stable hemoglobin levels. We analyzed pooled data from 13 studies with similar designs included in the Umbrella Continuous Erythropoietin Receptor Activator (C.E.R.A.) program to investigate the effects of continuous erythropoiesis receptor activator in clinically relevant subgroups of patients with chronic kidney disease and to determine whether the efficacy and safety outcomes demonstrated in the overall chronic kidney disease population are maintained in specific subgroups.

Methods

Data from 13 Phase III trials set up with similar design were retrospectively pooled for this analysis. Patients with chronic kidne

SUBMITTER: Locatelli F 

PROVIDER: S-EPMC4846713 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature