High-resolution (1) H-MRSI of the brain using SPICE: Data acquisition and image reconstruction.

ABSTRACT:

Purpose

To develop data acquisition and image reconstruction methods to enable high-resolution (1) H MR spectroscopic imaging (MRSI) of the brain, using the recently proposed subspace-based spectroscopic imaging framework called SPICE (SPectroscopic Imaging by exploiting spatiospectral CorrElation).

Theory and methods

SPICE is characterized by the use of a subspace model for both data acquisition and image reconstruction. For data acquisition, we propose a novel spatiospectral encoding scheme that provides hybrid data sets for determining the subspace structure and for image reconstruction using the subspace model. More specifically, we use a hybrid chemical shift imaging /echo-planar spectroscopic imaging sequence for two-dimensional (2D) MRSI and a dual-density, dual-speed

SUBMITTER: Lam F 

PROVIDER: S-EPMC4848237 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature