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RCGH: a comprehensive array-based genomic profile platform for precision medicine.


ABSTRACT:

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We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitates profiles interpretation and decision-making through sharable interactive visualizations.

Availability and implementation

The rCGH R package is available on bioconductor (under Artistic-2.0). The aCGH-viewer is available at https://fredcommo.shinyapps.io/aCGH_viewer, and the application implementation is freely available for installation at https://github.com/fredcommo/aCGH_viewer

Contact

frederic.commo@gustaveroussy.fr

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Commo F 

PROVIDER: S-EPMC4848396 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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Publications

rCGH: a comprehensive array-based genomic profile platform for precision medicine.

Commo Frederic F   Guinney Justin J   Ferté Charles C   Bot Brian B   Lefebvre Celine C   Soria Jean-Charles JC   André Fabrice F  

Bioinformatics (Oxford, England) 20151226 9


<h4>Unlabelled</h4>We present rCGH, a comprehensive array-based comparative genomic hybridization analysis workflow, integrating computational improvements and functionalities specifically designed for precision medicine. rCGH supports the major microarray platforms, ensures a full traceability and facilitates profiles interpretation and decision-making through sharable interactive visualizations.<h4>Availability and implementation</h4>The rCGH R package is available on bioconductor (under Artis  ...[more]

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