The impact of premorbid and current intellect in schizophrenia: cognitive, symptom, and functional outcomes.

ABSTRACT:

Background

Cognitive heterogeneity among people with schizophrenia has been defined on the basis of premorbid and current intelligence quotient (IQ) estimates. In a relatively large, community cohort, we aimed to independently replicate and extend cognitive subtyping work by determining the extent of symptom severity and functional deficits in each group.

Methods

A total of 635 healthy controls and 534 patients with a diagnosis of schizophrenia or schizoaffective disorder were recruited through the Australian Schizophrenia Research Bank. Patients were classified into cognitive subgroups on the basis of the Wechsler Test of Adult Reading (a premorbid IQ estimate) and current overall cognitive abilities into preserved, deteriorated, and compromised groups using both clinical a

SUBMITTER: Wells R 

PROVIDER: S-EPMC4849463 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature