Unknown

Dataset Information

0

Click-Crosslinked Injectable Gelatin Hydrogels.

ABSTRACT: Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for high viability of encapsulated cells, establishment of 3D elongated cell morphologies, and biodegradation when injected in vivo.

SUBMITTER: Koshy ST 

PROVIDER: S-EPMC4849477 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Click-Crosslinked Injectable Gelatin Hydrogels.

Koshy Sandeep T ST   Desai Rajiv M RM   Joly Pascal P   Li Jianyu J   Bagrodia Rishi K RK   Lewin Sarah A SA   Joshi Neel S NS   Mooney David J DJ  

Advanced healthcare materials 20160125 5

Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for high viability of encapsulated cells, establishment of 3D elongated cell morphologies, and biodegradation when injected in vivo. ...[more]

Similar Datasets

Unknown Enzymatically crosslinked gelatin-laminin hydrogels for applications in neuromuscular tissue engineering.
| S-EPMC7141910 | biostudies-literature
Unknown Self-healing injectable gelatin hydrogels for localized therapeutic cell delivery.
| S-EPMC8285007 | biostudies-literature
Unknown Injectable Cucurbit[8]uril-Based Supramolecular Gelatin Hydrogels for Cell Encapsulation.
| S-EPMC7286610 | biostudies-literature
Unknown Gelatin-Based Hydrogels Blended with Gellan as an Injectable Wound Dressing.
| S-EPMC6044880 | biostudies-literature
Unknown Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy.
| S-EPMC4828320 | biostudies-literature
Unknown Click-crosslinkable and photodegradable gelatin hydrogels for cytocompatible optical cell manipulation in natural environment.
| S-EPMC4598855 | biostudies-other
Unknown Injectable gelatin derivative hydrogels with sustained vascular endothelial growth factor release for induced angiogenesis.
| S-EPMC4293253 | biostudies-literature
Unknown Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection.
| S-EPMC8611911 | biostudies-literature
Unknown Physically Crosslinked Hydrogels Based on Poly (Vinyl Alcohol) and Fish Gelatin for Wound Dressing Application: Fabrication and Characterization.
| S-EPMC7465127 | biostudies-literature
Unknown Temporal and spatial distribution of macrophage phenotype markers in the foreign body response to glutaraldehyde-crosslinked gelatin hydrogels.
| S-EPMC4879875 | biostudies-literature