Retinal Nerve Fiber Layer Measures and Cognitive Function in the EPIC-Norfolk Cohort Study.

ABSTRACT:

Purpose

We examined the relationship between retinal nerve fiber layer (RNFL) thickness and cognitive function in a population of older British adults.

Methods

Participants of the European Prospective Investigation of Cancer (EPIC) Norfolk cohort study underwent ophthalmic and cognitive assessment. Measurements of RNFL thickness were made using the Heidelberg Retina Tomograph (HRT). Cognitive testing included a short form of the Mini-Mental State Examination (SF-MMSE), an animal naming task, a letter cancellation task, the Hopkins Verbal Learning Test (HVLT), the National Adult Reading Test (NART), and the Paired Associates Learning Test. Multivariable linear regression models were used to assess associations of RNFL thickness with cognitive test scores, adjusted for age, se

SUBMITTER: Khawaja AP 

PROVIDER: S-EPMC4849871 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature