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An immunology primer for computational modelers.

ABSTRACT: The immune system is designed to protect an organism from infection and damage caused by a pathogen. A successful immune response requires the coordinated function of multiple cell types and molecules in the innate and adaptive immune systems. Given the complexity of the immune system, it would be advantageous to build computational models to better understand immune responses and develop models to better guide the design of immunotherapies. Often, researchers with strong quantitative backgrounds do not have formal training in immunology. Therefore, the goal of this review article is to provide a brief primer on cellular immunology that is geared for computational modelers.

SUBMITTER: Hawse WF

PROVIDER: S-EPMC4850904 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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An immunology primer for computational modelers.

Hawse William F WF Morel Penelope A PA

Journal of pharmacokinetics and pharmacodynamics 20140920 5

The immune system is designed to protect an organism from infection and damage caused by a pathogen. A successful immune response requires the coordinated function of multiple cell types and molecules in the innate and adaptive immune systems. Given the complexity of the immune system, it would be advantageous to build computational models to better understand immune responses and develop models to better guide the design of immunotherapies. Often, researchers with strong quantitative background ...[more]

PMID: 25238901

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Dataset Information

An immunology primer for computational modelers.

Publications

An immunology primer for computational modelers.

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