Dimensionality and Genetic Correlates of Problem Behavior in Low-Income African American Adolescents.

ABSTRACT: Researchers have long observed that problem behaviors tend to cluster together, particularly among adolescents. Epidemiological studies have suggested that this covariation is due, in part, to common genetic influences, and a number of plausible candidates have emerged as targets for investigation. To date, however, genetic association studies of these behaviors have focused mostly on unidimensional models of individual phenotypes within European American samples. Herein, we compared a series of confirmatory factor models to best characterize the structure of problem behavior (alcohol and marijuana use, sexual behavior, and disruptive behavior) within a representative community-based sample of 592 low-income African American adolescents (50.3% female), ages 13 to 18. We further explored th

SUBMITTER: Latendresse SJ 

PROVIDER: S-EPMC4851603 | biostudies-literature | 2017 Nov-Dec

REPOSITORIES: biostudies-literature