Inter-individual variation in fronto-temporal connectivity predicts the ability to learn different types of associations.

ABSTRACT: The uncinate fasciculus connects portions of the anterior and medial temporal lobes to the lateral orbitofrontal cortex, so it has long been thought that this limbic fiber pathway plays an important role in episodic memory. Some types of episodic memory are impaired after damage to the uncinate, while others remain intact. Because of this, the specific role played by the uncinate fasciculus in episodic memory remains undetermined. In the present study, we tested the hypothesis that the uncinate fasciculus is involved in episodic memory tasks that have high competition between representations at retrieval. To test this hypothesis, healthy young adults performed three tasks: Experiment 1 in which they learned to associate names with faces through feedback provided at the end of each trial; E

SUBMITTER: Alm KH 

PROVIDER: S-EPMC4851884 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature