Epithelial ovarian cancer: the molecular genetics of epithelial ovarian cancer.

ABSTRACT:

Background

Epithelial ovarian cancer (EOC) remains one of the leading causes of cancer-related deaths among women worldwide, despite gains in diagnostics and treatments made over the last three decades. Existing markers of ovarian cancer possess very limited clinical relevance highlighting the emerging need for identification of novel prognostic biomarkers as well as better predictive factors that might allow the stratification of patients who could benefit from a more targeted approach.

Patients and methods

A summary of molecular genetics of EOC.

Results

Large-scale high-throughput genomic technologies appear to be powerful tools for investigations into the genetic abnormalities in ovarian tumors, including studies on dysregulated genes and aberrantly activated signa

SUBMITTER: Krzystyniak J 

PROVIDER: S-EPMC4852274 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature