Cognitive load and autonomic response patterns under negative priming demand in depersonalization-derealization disorder.

ABSTRACT: Previous studies have yielded evidence for cognitive processing abnormalities and alterations of autonomic functioning in depersonalization-derealization disorder (DPRD). However, multimodal neuroimaging and psychophysiology studies have not yet been conducted to test for functional and effective connectivity under cognitive stress in patients with DPRD. DPRD and non-referred control subjects underwent a combined Stroop/negative priming task, and the neural correlates of Stroop interference effect, negative priming effect, error rates, cognitive load span and average amplitude of skin conductance responses were ascertained for both groups. Evoked haemodynamic responses for basic Stroop/negative priming activations were compared. For basic Stroop to neutral contrast, patients with DPRD diff

SUBMITTER: Lemche E 

PROVIDER: S-EPMC4855951 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature