Perceived Stress Is Differentially Related to Hippocampal Subfield Volumes among Older Adults.

ABSTRACT:

Introduction

Chronic exposure to stress has been shown to impact a wide range of health-related outcomes in older adults. Despite extensive animal literature revealing deleterious effects of biological markers of stress on the dentate gyrus subfield of the hippocampus, links between hippocampal subfields and psychological stress have not been studied in humans. This study examined the relationship between perceived stress and hippocampal subfield volumes among racially/ethnically diverse older adults.

Methods and materials

Between July 2011 and March 2014, 116 nondemented participants were consecutively drawn from the Einstein Aging Study, an ongoing community-based sample of individuals over the age of 70 residing in Bronx, New York. All participants completed the Perceived

SUBMITTER: Zimmerman ME 

PROVIDER: S-EPMC4856349 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature