Persistent Symptoms of Dengue: Estimates of the Incremental Disease and Economic Burden in Mexico.

ABSTRACT: Dengue is mostly considered an acute illness with three phases: febrile, critical with possible hemorrhagic manifestations, and recovery. But some patients present persistent symptoms, including fatigue and depression, as acknowledged by the World Health Organization. If persistent symptoms affect a non-negligible share of patients, the burden of dengue will be underestimated. On the basis of a systematic literature review and econometric modeling, we found a significant relationship between the share of patients reporting persisting symptoms and time. We updated estimates of the economic burden of dengue in Mexico, addressing uncertainty in productivity loss and incremental expenses using Monte Carlo simulations. Persistent symptoms represent annually about US$22.6 (95% certainty level [C

SUBMITTER: Tiga DC 

PROVIDER: S-EPMC4856607 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature