Characterizing the epidemiology of perioperative transfusion-associated circulatory overload.

ABSTRACT:

Background

Transfusion-associated circulatory overload (TACO) is a leading cause of transfusion-related fatalities, but its incidence and associated patient and transfusion characteristics are poorly understood. To inform surgical transfusion practice and to begin mitigating perioperative TACO, the authors aimed to define its epidemiology.

Methods

In this retrospective cohort study, the medical records of adult patients undergoing noncardiac surgery with general anesthesia during 2004 or 2011 and receiving intraoperative transfusions were screened using an electronic algorithm for identification of TACO. Those patients who were screened as high probability for TACO underwent rigorous manual review. Univariate and multivariate analyses evaluated associations between patient a

SUBMITTER: Clifford L 

PROVIDER: S-EPMC4857710 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature