Chinese Herbal Medicine for Aspirin Resistance: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

To assess the effectiveness and safety of Chinese herbal medicine (CHM) for the treatment of aspirin resistance (AR).

Methods

A comprehensive research of seven electronic databases was performed for comparative studies evaluating CHM for AR. Two authors independently extracted data and assessed the methodological quality of the included trials using the Cochrane risk of bias tool. Data wasere synthesized by using RevMan 5.3 software. (PROSPERO Registration #CRD42015020182).

Results

18 randomized controlled trials (RCTs) involving 1,460 patients were included. 15 RCTs reported significant difference in the reduction of platelet aggregation rate (PAR) induced by adenosine diphosphate (ADP) (P<0.05), and 11 reported significant effect of CHM plus aspirin to re

SUBMITTER: Chen H 

PROVIDER: S-EPMC4859478 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature