AXIN2 is Associated With Papillary Thyroid Carcinoma.

ABSTRACT:

Background

Findings of recent studies have demonstrated a rapid increase of the incidence of papillary thyroid carcinoma (PTC), which accounts for nearly 80% of thyroid cancers.

Objectives

The aim of this study was to explore the association between AXIN2 gene polymorphism and papillary thyroid carcinoma (PTC).

Patients and methods

106 blood samples (56 PTC patients and 50 healthy controls) were drawn from China-Japan Union Hospital in Jilin province, China, during October 2010 to March 2011. A case-control study was designed to examine the association between AXIN2 and PTC. Seven tag single nucleotide polymorphisms (tag SNPs) in AXIN2 were selected and genotyped. Frequencies of different genotypes and alleles were analyzed between the patients and the controls, using

SUBMITTER: Liu X 

PROVIDER: S-EPMC4860511 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature