Neurobiology of Sensory Overresponsivity in Youth With Autism Spectrum Disorders.

ABSTRACT:

Importance

More than half of youth with autism spectrum disorders (ASDs) have sensory overresponsivity (SOR), an extreme negative reaction to sensory stimuli. However, little is known about the neurobiological basis of SOR, and there are few effective treatments. Understanding whether SOR is due to an initial heightened sensory response or to deficits in regulating emotional reactions to stimuli has important implications for intervention.

Objective

To determine differences in brain responses, habituation, and connectivity during exposure to mildly aversive sensory stimuli in youth with ASDs and SOR compared with youth with ASDs without SOR and compared with typically developing control subjects.

Design, setting, and participants

Functional magnetic resonance imaging

SUBMITTER: Green SA 

PROVIDER: S-EPMC4861140 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature