Carbapenem- and Colistin-Resistant Enterobacter cloacae from Delta, Colorado, in 2015.

ABSTRACT: Resistance to carbapenems in Enterobacteriaceae is a clinical problem of growing significance. Difficulty in treating multidrug-resistant Gram-negative organisms with conventional antibiotics has led to a renewed and increasing use of polymyxin compounds, such as colistin. Here, we report the isolation of carbapenem- and colistin-resistant Enterobacter cloacae from a polymicrobial lower extremity wound in an ambulatory patient. Whole-genome sequencing demonstrated the presence of chromosomal blaIMI-1 and blaAmpC, as well as numerous efflux pump genes.

SUBMITTER: Norgan AP 

PROVIDER: S-EPMC4862446 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature