Characterization of an IncA/C Multidrug Resistance Plasmid in Vibrio alginolyticus.

ABSTRACT: Cephalosporin-resistant Vibrio alginolyticus was first isolated from food products, with β-lactamases encoded by blaPER-1, blaVEB-1, and blaCMY-2 being the major mechanisms mediating their cephalosporin resistance. The complete sequence of a multidrug resistance plasmid, pVAS3-1, harboring the blaCMY-2 and qnrVC4 genes was decoded in this study. Its backbone exhibited genetic homology to known IncA/C plasmids recoverable from members of the family Enterobacteriaceae, suggesting its possible origin in Enterobacteriaceae.

SUBMITTER: Ye L 

PROVIDER: S-EPMC4862504 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature