Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation.

ABSTRACT: Nanogels have emerged as a versatile hydrophilic platform for encapsulation of guest molecules with a capability to respond to external stimuli that can be used for a multitude of applications. These are soft materials capable of holding small molecular therapeutics, biomacromolecules, and inorganic nanoparticles within their crosslinked networks, which allows them to find applications for therapy as well as imaging of a variety of disease conditions. Their stimuli-responsive behavior can be easily controlled by selection of constituent polymer and crosslinker components to achieve a desired response at the site of action, which imparts nanogels the ability to participate actively in the intended function of the carrier system rather than being passive carriers of their cargo. These proper

SUBMITTER: Soni KS 

PROVIDER: S-EPMC4862943 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature