Poor Adherence to Statin and Antihypertensive Therapies as Risk Factors for Fatal Stroke.

ABSTRACT:

Background

Poor adherence to medication regimens is common, potentially contributing to the occurrence of related disease.

Objectives

The authors sought to assess the risk of fatal stroke associated with nonadherence to statin and/or antihypertensive therapy.

Methods

We conducted a population-based study using electronic medical and prescription records from Finnish national registers in 1995 to 2007. Of the 58,266 hypercholesterolemia patients age 30+ years without pre-existing stroke or cardiovascular disease, 532 patients died of stroke (cases), and 57,734 remained free of incident stroke (controls) during the mean follow-up of 5.5 years. We captured year-by-year adherence to statin and antihypertensive therapy in both study groups and estimated the excess risk of

SUBMITTER: Herttua K 

PROVIDER: S-EPMC4863178 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature