Infant Gut Microbiota Development Is Driven by Transition to Family Foods Independent of Maternal Obesity.

ABSTRACT: The first years of life are paramount in establishing our endogenous gut microbiota, which is strongly affected by diet and has repeatedly been linked with obesity. However, very few studies have addressed the influence of maternal obesity on infant gut microbiota, which may occur either through vertically transmitted microbes or through the dietary habits of the family. Additionally, very little is known about the effect of diet during the complementary feeding period, which is potentially important for gut microbiota development. Here, the gut microbiotas of two different cohorts of infants, born either of a random sample of healthy mothers (n = 114), or of obese mothers (n = 113), were profiled by 16S rRNA amplicon sequencing. Gut microbiota data were compared to breastfeeding patterns

SUBMITTER: Laursen MF 

PROVIDER: S-EPMC4863607 | biostudies-literature | 2016 Jan-Feb

REPOSITORIES: biostudies-literature