The association between vascular endothelial growth factor gene polymorphisms and stroke: a meta-analysis.

ABSTRACT:

Objectives

Numerous studies have investigated the relationships between vascular endothelial growth factor (VEGF) gene polymorphisms and stroke. However, their findings remain controversial. The objective of this study was to evaluate the relationships between VEGF gene polymorphisms and stroke by a meta-analysis.

Materials and methods

The PubMed, Embase, China National Knowledge Infrastructure database, Wanfang Chinese database, and VIP Chinese database were systemically searched. Data were extracted by two independent reviewers, and pooled odds ratio (OR) with 95% confidence interval (CI) were calculated.

Results

Ten studies were included, including a total of 2331 cases and 1814 controls for +936C>T, 3040 cases and 2649 controls for -1154G>A. Under the dominant and

SUBMITTER: Wu T 

PROVIDER: S-EPMC4864291 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature