MicroRNA Regulation of Human Genes Essential for Influenza A (H7N9) Replication.

ABSTRACT: Influenza A viruses are important pathogens of humans and animals. While seasonal influenza viruses infect humans every year, occasionally animal-origin viruses emerge to cause pandemics with significantly higher morbidity and mortality rates. In March 2013, the public health authorities of China reported three cases of laboratory confirmed human infection with avian influenza A (H7N9) virus, and subsequently there have been many cases reported across South East Asia and recently in North America. Most patients experience severe respiratory illness, and morbidity with mortality rates near 40%. No vaccine is currently available and the use of antivirals is complicated due the frequent emergence of drug resistant strains. Thus, there is an imminent need to identify new drug targets for thera

SUBMITTER: Wolf S 

PROVIDER: S-EPMC4864377 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature