Heat Shock Proteins in Dermatophytes: Current Advances and Perspectives.

ABSTRACT: Heat shock proteins (HSPs) are proteins whose transcription responds rapidly to temperature shifts. They constitute a family of molecular chaperones, involved in the proper folding and stabilisation of proteins under physiological and adverse conditions. HSPs also assist in the protection and recovery of cells exposed to a variety of stressful conditions, including heat. The role of HSPs extends beyond chaperoning proteins, as they also participate in diverse cellular functions, such as the assembly of macromolecular complexes, protein transport and sorting, dissociation of denatured protein aggregates, cell cycle control, and programmed cell death. They are also important antigens from a variety of pathogens, are able to stimulate innate immune cells, and are implicated in acquired immuni

SUBMITTER: Martinez-Rossi NM 

PROVIDER: S-EPMC4864838 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature