Causes of Death in Adults with Mitochondrial Disease.

ABSTRACT:

Introduction

Mitochondrial diseases are a clinically, biochemically and genetically heterogeneous group of disorders with a variable age of onset and rate of disease progression. It might therefore be expected that this variation be reflected in the age and cause of death. However, to date, little has been reported regarding the 'end-of-life' period and causes of death in mitochondrial disease patients. For some specific syndromes, the associated clinical problems might predict the cause of death, but for many patients, it remains difficult to provide an accurate prognosis.

Aims

To describe a retrospective cohort of adult mitochondrial disease patients who had attended the NHS Highly Specialised Services for Rare Mitochondrial Diseases in Newcastle upon Tyne (UK), evaluate l

SUBMITTER: Barends M 

PROVIDER: S-EPMC4864865 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature