Thalamic Volume Is Reduced in Cervical and Laryngeal Dystonias.

ABSTRACT:

Background

Dystonia, a debilitating movement disorder characterized by abnormal fixed positions and/or twisting postures, is associated with dysfunction of motor control networks. While gross brain lesions can produce secondary dystonias, advanced neuroimaging techniques have been required to identify network abnormalities in primary dystonias. Prior neuroimaging studies have provided valuable insights into the pathophysiology of dystonia, but few directly assessed the gross volume of motor control regions, and to our knowledge, none identified abnormalities common to multiple types of idiopathic focal dystonia.

Methods

We used two gross volumetric segmentation techniques and one voxelwise volumetric technique (voxel based morphometry, VBM) to compare regional volume between

SUBMITTER: Waugh JL 

PROVIDER: S-EPMC4865047 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature