Pain and Laboratory Animals: Publication Practices for Better Data Reproducibility and Better Animal Welfare.

ABSTRACT: Scientists who perform major survival surgery on laboratory animals face a dual welfare and methodological challenge: how to choose surgical anesthetics and post-operative analgesics that will best control animal suffering, knowing that both pain and the drugs that manage pain can all affect research outcomes. Scientists who publish full descriptions of animal procedures allow critical and systematic reviews of data, demonstrate their adherence to animal welfare norms, and guide other scientists on how to conduct their own studies in the field. We investigated what information on animal pain management a reasonably diligent scientist might find in planning for a successful experiment. To explore how scientists in a range of fields describe their management of this ethical and methodologica

SUBMITTER: Carbone L 

PROVIDER: S-EPMC4865140 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature