Real-Time MRI-Guided Cardiac Cryo-Ablation: A Feasibility Study.

ABSTRACT:

Introduction

MRI-based ablation provides an attractive capability of seeing ablation-related tissue changes in real time. Here we describe a real-time MRI-based cardiac cryo-ablation system.

Methods

Studies were performed in canine model (n = 4) using MR-compatible cryo-ablation devices built for animal use: focal cryo-catheter with 8 mm tip and 28 mm diameter cryo-balloon. The main steps of MRI-guided cardiac cryo-ablation procedure (real-time navigation, confirmation of tip-tissue contact, confirmation of vessel occlusion, real-time monitoring of a freeze zone formation, and intra-procedural assessment of lesions) were validated in a 3 Tesla clinical MRI scanner.

Results

The MRI compatible cryo-devices were advanced to the right atrium (RA) and right ventricle (RV)

SUBMITTER: Kholmovski EG 

PROVIDER: S-EPMC4865432 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature