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Data on IL-17 production induced by plant lectins.


ABSTRACT: We reported in article da Silva et al. (2016) [2] that ArtinM induces the IL-17 production through interaction with CD4(+) T cells and stimulation of IL-23 and IL-1. Besides ArtinM, other plant lectins (PLs) induce IL-17 production by murine spleen cells. The IL-17 production induced by PLs was evaluated regarding the involvement of IL-23, IL-6, Th1-, and Th2-cytokines. Furthermore, the effect exerted TLR2, TLR4, and CD14 on the PLs׳ performance in the induction of IL-17 was examined. The current data were compared to the known ArtinM ability to induce Th17 immunity.

SUBMITTER: da Silva TA 

PROVIDER: S-EPMC4865662 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature