Drug repurposing in pharmaceutical industry and its impact on market access: market access implications.

ABSTRACT: Drug repurposing is a group of development strategies employed in order to overcome some of the hurdles innate to drug research and development. Drug repurposing includes drug repositioning, reformulation and combination. This study aimed to identify the determinants of successful market access outcome for drug repurposing in the United States of America (USA) and in Europe. The case studies of repurposing strategies were identified through a systematic review of the literature. Price information and reimbursement conditions for all the case studies were collected mainly through access of public datasources. A list of attributes that could be associated with market access outcome (price level and reimbursement conditions) was developed, discussed, and validated by an external expert group.

SUBMITTER: Murteira S 

PROVIDER: S-EPMC4865758 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature