The Cognition and Affect after Stroke - a Prospective Evaluation of Risks (CASPER) study: rationale and design.

ABSTRACT:

Background

Cognitive impairment and neuropsychiatric syndromes, like depression and apathy, are frequent residual consequences of stroke. These have a large impact on quality of life and long-term prognosis. Several factors are involved in the development of these residual syndromes, although their exact role and their interrelationships remain still rather unclear. The Cognition and Affect after Stroke: a Prospective Evaluation of Risks (CASPER) study has been primarily designed to examine whether stroke-specific (e.g. lesion location, volume, type, severity), cerebrovascular and neurodegenerative (e.g. white matter changes, atrophy, microbleeds, perivascular spaces), inflammatory, endothelial, and (epi)genetic markers are associated with cognitive impairment, post-stroke depressi

SUBMITTER: Douven E 

PROVIDER: S-EPMC4866410 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature