Impact of very low physical activity, BMI, and comorbidities on mortality among breast cancer survivors.

ABSTRACT: The purpose of this study was to examine post-diagnosis BMI, very low physical activity, and comorbidities, as predictors of breast cancer-specific and all-cause mortality. Data from three female US breast cancer survivor cohorts were harmonized in the After Breast Cancer Pooling Project (n = 9513). Delayed entry Cox proportional hazards models were used to examine the impact of three post-diagnosis lifestyle factors: body mass index (BMI), select comorbidities (diabetes only, hypertension only, or both), and very low physical activity (defined as physical activity <1.5 MET h/week) in individual models and together in multivariate models for breast cancer and all-cause mortality. For breast cancer mortality, the individual lifestyle models demonstrated a significant association with very l

SUBMITTER: Nelson SH 

PROVIDER: S-EPMC4866506 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature