Aging modulates the oscillatory dynamics underlying successful working memory encoding and maintenance.

ABSTRACT: Working memory is central to the execution of many daily functions and is typically divided into three phases: encoding, maintenance, and retrieval. While working memory performance has been repeatedly shown to decline with age, less is known regarding the underlying neural processes. We examined age-related differences in the neural dynamics that serve working memory by recording high-density magnetoencephalography (MEG) in younger and older adults while they performed a modified, high-load Sternberg working memory task with letters as stimuli. MEG data were evaluated in the time-frequency domain and significant oscillatory responses were imaged using a beamformer. A hierarchical regression was performed to investigate whether age moderated the relationship between oscillatory activity an

SUBMITTER: Proskovec AL 

PROVIDER: S-EPMC4867257 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature