LOGIQA: a database dedicated to long-range genome interactions quality assessment.

ABSTRACT:

Background

Proximity ligation-mediated methods are essential to study the impact of three-dimensional chromatin organization on gene programming. Albeit significant progress has been made in the development of computational tools that assess long-range chromatin interactions, next to nothing is known about the quality of the generated datasets.

Method

We have developed LOGIQA ( www.ngs-qc.org/logiqa ), a database hosting quality scores for long-range genome interaction assays, accessible through a user-friendly web-based environment.

Results

Currently, LOGIQA harbors QC scores for >900 datasets, which provides a global view of their relative quality and reveals the impact of genome size, coverage and other technical aspects. LOGIQA provides a user-friendly dataset que

SUBMITTER: Mendoza-Parra MA 

PROVIDER: S-EPMC4868109 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature