Ontology highlight
ABSTRACT:
SUBMITTER: Jolly AL
PROVIDER: S-EPMC4868501 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Cell reports 20160107 3
Long-distance intracellular transport of organelles, mRNA, and proteins ("cargo") occurs along the microtubule cytoskeleton by the action of kinesin and dynein motor proteins, but the vast network of factors involved in regulating intracellular cargo transport are still unknown. We capitalize on the Drosophila melanogaster S2 model cell system to monitor lysosome transport along microtubule bundles, which require enzymatically active kinesin-1 motor protein for their formation. We use an automat ...[more]