Demographic and clinical features of inclusion body myositis in North America.

ABSTRACT:

Introduction

Few studies of the demographics, natural history, and clinical management of inclusion body myositis (IBM) have been performed in a large patient population. To more accurately define these characteristics, we developed and distributed a questionnaire to patients with IBM.

Methods

A cross-sectional, self-reporting survey was conducted.

Results

The mean age of the 916 participants was 70.4 years, the male-to-female ratio was 2:1, and the majority reported difficulty with ambulation and activities of daily living. The earliest symptoms included impaired use and weakness of arms and legs. The mean time from first symptoms to diagnosis was 4.7 years. Half reported that IBM was their initial diagnosis. A composite functional index negatively associated with ag

SUBMITTER: Paltiel AD 

PROVIDER: S-EPMC4869122 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature