Emerging Concepts in Paracrine Mechanisms in Regenerative Cardiovascular Medicine and Biology.

ABSTRACT: In the past decade, substantial evidence supports the paradigm that stem cells exert their reparative and regenerative effects, in large part, through the release of biologically active molecules acting in a paracrine fashion on resident cells. The data suggest the existence of a tissue microenvironment where stem cell factors influence cell survival, inflammation, angiogenesis, repair, and regeneration in a temporal and spatial manner.

SUBMITTER: Hodgkinson CP 

PROVIDER: S-EPMC4874329 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature