Coffee Consumption and the Risk of Colorectal Cancer.

ABSTRACT:

Background

Coffee contains several bioactive compounds relevant to colon physiology. Although coffee intake is a proposed protective factor for colorectal cancer, current evidence remains inconclusive.

Methods

We investigated the association between coffee consumption and risk of colorectal cancer in 5,145 cases and 4,097 controls from the Molecular Epidemiology of Colorectal Cancer (MECC) study, a population-based case-control study in northern Israel. We also examined this association by type of coffee, by cancer site (colon and rectum), and by ethnic subgroup (Ashkenazi Jews, Sephardi Jews, and Arabs). Coffee data were collected by interview using a validated, semi-quantitative food frequency questionnaire.

Results

Coffee consumption was associated with 26% lower o

SUBMITTER: Schmit SL 

PROVIDER: S-EPMC4874555 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature