Discordance between patient and physician assessments of global disease activity in rheumatoid arthritis and association with work productivity.

ABSTRACT:

Background

Discordance between patient and physician ratings of rheumatoid arthritis (RA) severity occurs in clinical practice and correlates with pain scores and measurements of joint disease. However, information is lacking on whether discordance impacts patients' ability to work. We evaluated the discordance between patient and physician ratings of RA disease activity before and after treatment with etanercept and investigated the associations between discordance, clinical outcomes, and work productivity.

Methods

In the PRESERVE clinical trial, patients with moderate RA received open-label etanercept 50 mg once weekly plus methotrexate for 36 weeks. Baseline and week-36 disease characteristics and clinical and work productivity outcomes were categorized according to week-

SUBMITTER: Smolen JS 

PROVIDER: S-EPMC4875609 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature