Antiemetics: American Society of Clinical Oncology clinical practice guideline update.

ABSTRACT:

Purpose

To update the American Society of Clinical Oncology (ASCO) guideline for antiemetics in oncology.

Methods

A systematic review of the medical literature was completed to inform this update. MEDLINE, the Cochrane Collaboration Library, and meeting materials from ASCO and the Multinational Association for Supportive Care in Cancer were all searched. Primary outcomes of interest were complete response and rates of any vomiting or nausea.

Results

Thirty-seven trials met prespecified inclusion and exclusion criteria for this systematic review. Two systematic reviews from the Cochrane Collaboration were identified; one surveyed the pediatric literature. The other compared the relative efficacy of the 5-hydroxytryptamine-3 (5-HT(3)) receptor antagonists.

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SUBMITTER: Basch E 

PROVIDER: S-EPMC4876353 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature