Deceased-donor split-liver transplantation in adult recipients: is the learning curve over?

ABSTRACT:

Background

Infants have the highest wait-list mortality of all liver transplantation candidates. Deceased-donor split-liver transplantation, a technique that provides both an adult and pediatric graft, might be the best way to decrease this disproportionate mortality. Yet concern for an increased risk to adult split recipients has discouraged its widespread adoption. We aimed to determine the current risk of graft failure in adult recipients after split-liver transplantation.

Study design

United Network for Organ Sharing data from 62,190 first-time adult recipients of deceased-donor liver transplants (1995-2010) were analyzed (889 split grafts). Bivariate risk factors (p < 0.2) were included in Cox proportional hazards models of the effect of transplant type on graft failure

SUBMITTER: Cauley RP 

PROVIDER: S-EPMC4876853 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature