Diabetic gastroparesis alters the biomagnetic signature of the gastric slow wave.

ABSTRACT:

Background

Gastroparesis is characterized by delayed gastric emptying without mechanical obstruction, but remains difficult to diagnose and distinguish from other gastrointestinal (GI) disorders. Gastroparesis affects the gastric slow wave, but non-invasive assessment has been limited to the electrogastrogram (EGG), which reliably characterizes temporal dynamics but does not provide spatial information.

Methods

We measured gastric slow wave parameters from the EGG and magnetogastrogram (MGG) in patients with gastroparesis and in healthy controls. In addition to dominant frequency (DF) and percentage power distribution (PPD), we measured the propagation velocity from MGG spatiotemporal patterns and the percentage of slow wave coupling (%SWC) from EGG.

Key results

No si

SUBMITTER: Bradshaw LA 

PROVIDER: S-EPMC4877247 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature