Ontology highlight
ABSTRACT:
SUBMITTER: Heaton NS
PROVIDER: S-EPMC4878455 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Immunity 20160101 1
Viruses are obligate parasites and thus require the machinery of the host cell to replicate. Inhibition of host factors co-opted during active infection is a strategy hosts use to suppress viral replication and a potential pan-antiviral therapy. To define the cellular proteins and processes required for a virus during infection is thus crucial to understanding the mechanisms of virally induced disease. In this report, we generated fully infectious tagged influenza viruses and used infection-base ...[more]