Hypoglycemia after antimicrobial drug prescription for older patients using sulfonylureas.

ABSTRACT:

Importance

Certain antimicrobial drugs interact with sulfonylureas to increase the risk of hypoglycemia.

Objective

To determine the risk of hypoglycemia and associated costs in older patients prescribed glipizide or glyburide who fill a prescription for an antimicrobial drug.

Design, setting, and participants

This was a retrospective cohort study of Texas Medicare claims from 2006 to 2009 for patients 66 years or older who were prescribed glipizide or glyburide and who also filled a prescription for 1 of the 16 antimicrobials most commonly prescribed for this population.

Methods

We assessed hypoglycemia events and associated Medicare costs in patients prescribed 1 of 7 antimicrobial agents thought to interact with sulfonylureas, using noninteracting antimicrobi

SUBMITTER: Parekh TM 

PROVIDER: S-EPMC4878670 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature