Subclinical carotid atherosclerosis and neurocognitive function in an urban population.

ABSTRACT:

Background and aims

Examine age, sex, race, and socioeconomic status as modifiers of the association between carotid intimal medial thickness (IMT) and neurocognitive performance in a socioeconomically diverse, biracial, urban, adult population.

Methods

Participants were 1712 community-dwelling adults (45% men, 56% African-American, 38% below poverty threshold, aged 30-64 years) enrolled in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study. Participants underwent initial carotid ultrasonography followed by cognitive testing on up to two occasions over 4 years. Mixed-effects regression analyses were adjusted for demographic, behavioral, and biomedical covariates.

Results

Significant cross-sectional IMT × race × poverty interactions wer

SUBMITTER: Wendell CR 

PROVIDER: S-EPMC4879049 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature