In vivo Sarcomere Lengths and Sarcomere Elongations Are Not Uniform across an Intact Muscle.

ABSTRACT: Sarcomere lengths have been a crucial outcome measure for understanding and explaining basic muscle properties and muscle function. Sarcomere lengths for a given muscle are typically measured at a single spot, often in the mid-belly of the muscle, and at a given muscle length. It is then assumed implicitly that the sarcomere length measured at this single spot represents the sarcomere lengths at other locations within the muscle, and force-length, force-velocity, and power-velocity properties of muscles are often implied based on these single sarcomere length measurements. Although, intuitively appealing, this assumption is yet to be supported by systematic evidence. The objective of this study was to measure sarcomere lengths at defined locations along and across an intact muscle, at diff

SUBMITTER: Moo EK 

PROVIDER: S-EPMC4879144 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature